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Each serving of Optimum Nutrition Opti-Men delivers a high-potency dose of 75+ ingredients, via their Nutrient Optimization System. This includes 1 gram of an Amino Men Blend, containing amino acids such as L-Glutamine, L-Arginine, and all three BCAAs (L-Leucine, L-Isoleucine, L-Valine).
But with 2500% of your Vitamin B6 RDA per 3 tablet serving, how do you know if this is a safe dose? What if you’re already taking a protein powder with its own multivitamin complex?
In this review we compare O.N. Optimum-Men to two of the best multivitamins on the market; Dr. Tobias Vitality, and One-A-Day Men’s Health Formula. This includes ingredients, dosages, cost per serving, price, and customer feedback from the thousands of reviews on Amazon.
We’ve also added recommendations for the best protein powder to combine with Opti-Men to balance your vitamin, mineral, Omega-3, probiotic, and protein intake.
Optimum Nutrition Opti-Men Ingredients

Compared to their Opti-Women supplement, the levels of vitamins and minerals found in Opti-Men have been increased. Generally the RDA for vitamins and minerals is based on age rather than gender, but it’s the added ingredients that make this particular multivitamin better suited to men.
The Viri Men Blend contains 50 mg of natural ingredients designed to support healthy testosterone levels. This includes Saw Palmetto Extract, which may boost testosterone (T) by preventing it from converting into dihydrotestosterone (DHT).
But there’s little scientific evidence to prove the ingredients in this blend have any real health benefits. Some anecdotal evidence suggests Damiana’s active compounds may block the conversion of testosterone to estrogen. But we’ve seen no evidence to back this up.
It’s a similar story with the 100 mg of Phyto Men Blend. Several studies have found green tea to have fat burning benefits, and there is some evidence to suggest hesperidin can help with blood vessel conditions, such as poor circulation.
Unfortunately, these sources also recommend consuming 500 mg of hesperidin daily to see any real benefit, which is well below the amount contained in Optimum Nutrition Opti-Men.
What’s in Optimum Nutrition Opti-Men?
Ingredient | Amount per Serving |
---|---|
Vitamin A | 10,000 IU |
Vitamin C | 300 mg |
Vitamin D | 1,500 IU |
Vitamin E | 200 IU |
Vitamin K | 75 mcg |
Thiamin | 75 mg |
Riboflavin | 75 mg |
Niacin | 75 mg |
Vitamin B6 | 50 mg |
Folic Acid | 600 mcg |
Vitamin B12 | 100 mcg |
Biotin | 300 mcg |
Pantothenic Acid | 75 mg |
Calcium | 50 mg |
Iodine | 150 mcg |
Magnesium | 80 mg |
Zinc | 15 mg |
Also contains:
-
Amino Men Blend 1 g
L-Arginine, L-Glutamine, L-Valine, L-Leucine, L-Isoleucine, L-Cystine, L-Lysine HCI, L-Threonine -
Phyto Men Blend 100 mg
Green Tea Powder, Hesperidin Complex
Fruit Blend [Grape Extract, Apple Powder, Blueberry Powder, Papaya Powder, Black Currant Powder, Orange Powder, etc.] -
Viri Men Blend 50 mg
Saw Palmetto Extract, Damiana Extract, Panax Ginseng Extract, Ginkgo Biloba Powdered Extract, Pumpkin Extract, Raw Oyster Concentrate -
Enzyme Blend 50 mg
Papain, Bromelain, Alpha Amylase, Lipase - Alpha Lipoic Acid 25 mg
3 tablets per serving
- Amino Blend: 8 key free-form acids (including Arginine, Glutamine and BCAAs), the building blocks of muscle protein
- Viri-Blend: 8 exotic botanicals and marine concentrates
- Phyto-Blend: Over 20 fruit and vegetable concentrates
- Enzy-Blend: 4 specific enzymes
- 350+ Milligrams B-Complex Vitamins
- 25 Vitamins & Essential Minerals
- 1 Gram of Free Form Amino Acids
- 100 MG Phyto Blend (Phytonutrients)
- 1,500 IU of Vitamin D
- ON’s Nutrient Optimization System for active men stacks 75+ active ingredients into a 3-tablet serving
Health benefits of Optimum Nutrition Opti-Men
Our recently updated multivitamin guide contains a complete list of health benefits associated with the vitamins found in Opti-Men.
When is the best time to take it?
Recommended use
As a dietary supplement for men, consume 3 tablets daily with food.
Opti-Men vs. Dr. Tobias Vitality
Opti-Men vs. One-A-Day Men’s Health Formula
What sizes are available?
With a serving size of 3 tablets, each bottle provides you with either 30, 50, or 80 servings.
At the time of writing this review, the best value for money comes from the bottle of 150 tablets. Each serving was priced at $0.44, compared to $0.50 per serving with the bottle of 90 tablets. We always recommend calculating the average cost per serving, across all sizes, before making a final buying decision.
Save money with Amazon
If you’re looking to save money on your monthly supplement order, you might want to consider the Amazon Subscribe & Save program.
Subscribe & Save allows you to unlock savings of up to 15% on a wide range of sports nutrition products, including Optimum Nutrition Opti-Men.
You can save 5% with a subscription to 1 product, or save the full 15% by subscribing to 5 products, provided they’re all delivered to the same address. The delivery schedule can be set from monthly, up to once every 6 months.
Although 5 products might sound a lot, if you already supplement with a protein powder, multivitamin, creatine, BCAA, and glutamine, the savings can soon add up. But it’s best to order before you run out of your current supplements, because Amazon set the day of the month each order is sent (same day each month e.g. 14th.).
Who are Optimum Nutrition?
With over 30 years in the sports nutrition industry, Optimum Nutrition currently produces some of the bestselling sports nutrition products in the world. These have been designed to improve your strength and recovery, health and wellness, and help increase your protein intake, such as their Gold Standard 100% Whey.
To find out more about their protein powders, bars, ready to drinks, BCAAs, glutamine, pre-workout supplements, creatine, multivitamins, and weight loss products, we recommend our Optimum Nutrition buying guide. This includes a summary of the health benefits you can expect from each product, which sizes and flavors are available, and dosages for the top ingredients.
We’ve also added in-depth reviews and comparisons with other top rated nutrition companies, to guarantee you only buy the best supplement for your fitness goals.
Optimum Nutrition Opti-Men Review Summary
So, is Opti-Men really the best men's multivitamin?
It's certainly not the cheapest. One-A-Day Men's Multivitamin cost a fraction of what Opti-Men did at the time of writing this review ($0.07 per serving vs. $0.44).
But the high-potency formula really sets it apart from the competition, with higher than average levels of most key vitamins and minerals. This means it's still excellent value for money.
The scientific evidence may be harder to come by to validate the proprietary formulas, such as the Phyto Men Blend and Viri Men Blend. But they really don't seem to add much to the price when you compare the ingredients to something like GNC Mega Men Sport.
Overall, Opti-Men offers far more vitamins and minerals per serving than some of the top men's multivitamins from Vitafusion and Centrum.
Optimum Nutrition are also a trusted company with a great track record for quality and customer service. Highly recommended.
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